curriculum vitae

Since 2001 I have a permanent position as staff researcher at the “Istituto di Cibernetica Eduardo Caianiello” CNR-ICIB. I took my degree in biology cum laude in 1990 at the “University of Naples Federico II”. As graduate student I worked at a research project concerning the study of genetic basis of Drosophila oogenesis. As postgraduate student I moved from animal genetics to the field of neuroscience. From 1991 to 1994 under the supervision of Dr. U. Di Porzio, at Institute of Genetics and Biophysics (CNR-IGB), I was involved in research projects aimed to describe, with cellular and molecular approaches, the development of nigro-striatal dopaminergic pathway and the construction of a neuronal cell line. In 1995 at CNR-IGB, I worked for two years as CNR young researcher, at a project concerning the genetic dissection of early stages of animal development. From 1997 to 2000 I was host researcher at CNR-ICIB. At present, my scientific interests are focused on the development, physiology and evolution of the nervous system. I work at interdisciplinary research projects aimed to develop new tools committed to the study of gene function using animal models and bio-nanotechnologies. I'm author of 21 papers published on peer review International journals.


2007-2015: go to  NanoBiomolecular Group Publication page

Additional Publications

Ruocco LA, Treno C, Gironi Carnevale UA, Arra C, Boatto G, Pagano C, Tino A, Nieddu M, Michel M, Prikulis I, Carboni E, de Souza Silva MA, Huston JP, Sadile AG, Korth C. Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum. Amino Acids. 2015 Mar;47(3):637-50

Ruocco LA, Treno C, Gironi Carnevale UA, Arra C, Mattern C, Huston JP, de Souza Silva MA, Nikolaus S, Scorziello A, Nieddu M, Boatto G, Illiano P, Pagano C, Tino A, Sadile AG. Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum. Amino Acids. 2014 Sep;46(9):2105-22

Ruocco LA, Treno C, Gironi Carnevale UA, Arra C, Boatto G, Nieddu M, Pagano C, Illiano P, Barbato F, Tino A et al: Prepuberal Stimulation of 5-HT7-R by LP-211 in a Rat Model of Hyper-Activity and Attention-Deficit: Permanent Effects on Attention, Brain Amino Acids and Synaptic Markers in the Fronto-Striatal Interface. PLoS One 2014, 9(4):e83003.

Romano E, Ruocco LA, Nativio P, Lacivita E, Ajmone-Cat MA, Boatto G, Nieddu M, Tino A, Sadile AG, Minghetti L et al: Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats. Reviews in the neurosciences 2014, 25(3): doi: 10.1515/revneuro-2014-0007.

Pierobon P, Sogliano C, Minei R, Tino A, Porcu P, Marino G, Tortiglione C, Concas A. Putative NMDA receptors in Hydra: a biochemical and functional study. Eur J Neurosci. (2004) 20, 2598-604. PubMed PMID: 15548203.

Pierobon P, Minei R, Porcu P, Sogliano C, Tino A, Marino G, Biggio G, Concas A. Putative glycine receptors in Hydra: a biochemical and behavioural study. Eur  J Neurosci. (2001) 14, 1659-66. PubMed PMID: 11860460.

Colucci-D'Amato GL, Tino A, Pernas-Alonso R, ffrench-Mullen JM, di Porzio U. Neuronal and glial properties coexist in a novel mouse CNS immortalized cell line. Exp Cell Res. (1999) 252, 383-91. PubMed PMID: 10527628.

Pistillo D, Manzi A, Tino A, Boyl PP, Graziani F, Malva C. The Drosophila melanogaster lipase homologs: a gene family with tissue and developmental specific expression. J Mol Biol. (1998) 276, 877-85. PubMed PMID: 9566193.

Cangiano G, Ambrosini M, Patruno A, Tino A, Buttiglione M, Gennarini G. Functional organization of the promoter region of the mouse F3 axonal glycoprotein gene. Brain Res Mol Brain Res. (1997) 48, 279-90. PubMed PMID: 9332725.

Perrone-Capano C, Tino A, Amadoro G, Pernas-Alonso R, di Porzio U. Dopamine transporter gene expression in rat mesencephalic dopaminergic neurons is increased by direct interaction with target striatal cells in vitro. Brain Res Mol Brain Res. (1996) 39,160-6. PubMed PMID: 8804724.

Perrone-Capano C, Tino A, di Porzio U. Target cells modulate dopamine transporter gene expression during brain development. Neuroreport. (1994) 5,1145-8. PubMed PMID: 7521683.

Gigliotti S, Cavaliere V, Manzi A, Tino A, Graziani F, Malva C. A membrane guanylate cyclase Drosophila homolog gene exhibits maternal and zygotic expression. Dev Biol. (1993) 159, 450-61. PubMed PMID: 8104831.

Malva C, Graziani F, Cavaliere V, Manzi A, Tino A. Genetic and molecular analysis of maternal information in region 32 of Drosophila melanogaster. Mol Reprod Dev. (1991) 28, 307-17. Review. PubMed PMID: 1901715.

Tino A, Graziani F, Di Nocera PP. A cDNA clone homologous to Drosophila F elements from an imaginal discs poly(A)+ library. Biochim Biophys Acta. (1990) 1087, 262-3. PubMed PMID: 1699608.


Family name, First name:                Tino, Angela

Date of birth:                                 February, 24th 1964

Address                                        Istituto di Scienze applicate e sistemi intelligenti“E.Caianiello”

                                                    Via Campi Flegrei 34- 80078 Pozzuoli


phone                                           +39 081 8675253