PERSONAL INFORMATION
Family name, First name:                                                        Tortiglione, Claudia
Researcher unique identifier :                                              Scopus Author ID: 6506714393, 
                                                                                        ORCID: /0000-0003-1447-7611  
Date of birth:                                                                         June, 30th 1969

Address                                                                                Istituto di Scienze applicate e sistemi intelligenti “E.Caianiello”
                                                                                            Via Campi Flegrei 34- 80078 Pozzuoli,                
phone                                                                                   +39 081 8675306 

email                                                                                     c.tortiglione@isasi.cnr.it
                                                                                            claudia.tortiglione@cnr.it
EDUCATION
Ph.D, University of Naples, Italy, 2003
Degree in Biology, (110/110,with Honours), University of Naples, Italy, 1992

Appointments
2003-current: Staff researcher at Istituto di Scienze applicate e sistemi intelligenti “E.Caianiello” (formerly Istituto di Ciberenetica), Consiglio Nazionale delle Ricerche, Pozzuoli, Italy

2001-2003:   Staff researcher at Istituto di Genetica Vegetale, Portici, Italy

1999-2002: PhD program funded by University of Naples, Dept. of Plant, Soil and Environmental Sciences, Faculty of Agronomy, Portici. Evaluation of the insecticidal activity of insect peptides by expression in plant systems. PhD tutor: Prof. Rosa Rao

1997-1999:  Research Assistant, funded by EU, at Dept. Plant, Soil and Environmental Sciences, Faculty of Agronomy, Portici; hired to work on the EU FP4 project “New Signalling Insect Peptides for crop protection”

1996-1997:  Research Assistant, funded by CNR, at Istituto di Genetica e Biofisica (IGB-CNR), Consiglio Nazionale delle Ricerche, Naples, to work on the project: "Plant genetic resistance to biotic and abiotic stresses“

1994-1996: Visiting Scholar, funded by EU program “Human capital and mobility” and by European Science Foundation (03-05/1996) held at Institute of Cell and Molecular Biology, University of Edinburgh, research group led by Prof. Mary Bownes: “Evolutionary approaches to study sex specific genes in dipteran species”

1993-1994: Graduate Research Assistant, funded by CNR, at IGB-CNR, Naples, working on “Molecular bases of germ cell differentiation in Drosophila melanogaster” 

1991-1992: Internship at IGB-CNR, Naples, group headed by Dr. F.Graziani and C.Malva. Experimental thesis: “Interaction between somatic and germ cell line during oogenesis of D.melanogaster: role of hold up gene.
Research Grants Secured (International)

H2020-MSCA-IF-2014 - Beneficiary and project coordinator. Profiling gene expression in Hydra vulgaris following Gold Nanoparticle-mediated hyperthermia (2015- 2017)|Grant number: 660228 to Dr. Maria Moros

NanoSciERAnet project NANOTRUCK: “Multifunctional gold nanoparticles for gene therapy” (2009-2012). Leader of the Italian Research Unit

ITALY-ISRAEL Joint Innovation Program for Scientific and Technological Cooperation in R&D
Project: “Impact of engineered nanoparticles on aquatic invertebrates: from nanoecotoxicology to advanced fluorescence imaging” (2012-2014). Leader of the  Italian Research Unit      

PROJECT MANAGEMENT RESPONSIBILITY
2010-2012	Annual and final Financial reporting for NanoSciERA net project “Nanotruck”
2012-2014	Annual and final Financial reporting for ITALY-ISRAEL Joint Innovation Program R&D 
                                                                             
INSTITUTIONAL RESPONSIBILITIES
Member of Committes For selection of CNR temporary positions on 04-2013, 12-2009, 02-2006

Program Committee member 

CIMTEC 2020, 9th Forum on New Materials. International Advisory Board, Symposium FO, Biological, Biohybrid And Bioinspired Materials: From Electronics And Photonics To Medicine. Montecatini Terme, 20-23 June 2020
CIMTEC 2018, 8th Forum on New Materials. International Advisory Board, Symposium Fl, Biological, Biohybrid And Bioinspired Materials: From Electronics And Photonics To Medicine. Perugia 10-14 June 2018
SPIE Photonic West: Colloidal Nanocrystals for Biomedical Applications. San Francisco CA. 2012 (Conference VII, n.8232), 2013 (Conference VIII 8595), 2014 (Conference IX, n 8955), 2015 (Conference X n 9338), 2016 (Conference XI n 9722); 2017 (Conference XII n 10078); 2018 (Conference XIII n 10507)

Conference session chair 
Material Research Society, Fall Meeting. 28-11 2017 Symposium BM03, Session BM03.03: Biophotonic structures and structural colors I. Boston, MA
SPIE Photonic West NanoBiophotonic Conference VII, n.8232, Session 2: Loading of Cells with Nanoparticles and Toxic Effects, San Francisco. 23-01-2012

Member of PhD evaluation committees
 -PhD in Chimie Biologie, Universitè Grenoble Alpes- Ecole de doctorale Chimie et Science du Vivant, 12-06-2016; PhD in Medical Biotechnology
- Scuola dottorato Scienze biotecnologiche , University of Naples 29-04-2013 
COMMISSIONS OF TRUST
From 2018	    Academic Editor PLOS ONE
From 2015	    Review Editor Frontiers in Bioengineering and Biotechnology
2013-2014     Review Board Conference Biomedical Engineering and Biotechnology
2010- to date Reviewer for following journals:
            ACS Nano, Biomaterials, Environmental Science Toxicology, Journal of Hazardous Materials, Advanced Health                       Materials, Nanomedicine, Nanotechnology, Nanotoxicology, Bioassay, Biomaterilas, Avdanced Biosystems, Small, Science Advanced Materials, Science and Technology of Advanced Materials, Nanotheranostic, Journal of Molecular Science, Current Pharmaceutical Design, Cancer research Frontiers, Journal Nanobiotechnology, Nano Biomedicine and Engineering, Current Medicinal Chemistry, Folia Biologica 

External expert evaluator for international PhD programs
2017
- Universidad de Pias Vasco, Material science, Basque Country, Spain 
- Universitat autonoma de Barcelona, Institut Ciència de Materials de Barcelona
- Universitè Grenoble Alpes- Ecole de doctorale Chimie et Science du Vivant

Project evaluator
2019    	External reviewer National Science Centre (Narodowe Centrum Nauki - NCN Poland) Funding Scheme “Preludium”
2018 	Panel member  (Chemical Science) and reviewer FTC Stimulus of Scientific Employment, Individual Support -
2015	        External reviewer (Chemical Science) FTC investigator grant. Fundação para a Ciência e a Tecnologia 
2013    	External reviewer FIRB "Futuro in Ricerca", Italian Ministry of Research and University 
2012	        German-Israeli Foundation for Scientific Research and Development

2017	        School Director
             1st International school on Nano-tooling@ScienceApp: Manipulating, shaping and functionalizing the matter.         Pozzuoli, 30-31 March 2017

TEACHING EXPERTISES 

2018-2019     Working experience for secondary High school (art. 1 D. Lgs. 77/05). Project: “BLABLAB”: LABriola in           LABoratorio per la diffusione della cultura scientifica, 2nd edition. Role: External tutor, 40 working hours, n.40 alumni Liceo Scientifico A.Labriola, November 2018 -May 2019 at Istituto Scienze applicate e sistemi intelligenti, CNR.
2017-2018      Working experience for secondary High school (art. 1 D. Lgs. 77/05). Project: “BLABLAB”: LABriola in LABoratorio per la diffusione della cultura scientifica. Role: External tutor, 40 working hours, n.26 alumni Liceo Scientifico A.Labriola, November 2017 at Istituto Scienze applicate e sistemi intelligenti, CNR.
2013-2017	Theoretical-practical course, School in Embryology and Developmental Biology, Univ Naples, 4 h course/year 
3-05- 2017	Educational programme for high school teacher, organized by Accademia Nazionale dei Lincei, Polo di Benevento, Corso di scienze. Università del Sannio (BN) 
05-2011 	PhD School Biotechnological Science (cycle XXV), Training course “Nanotechnological tools for investigation of basic and applied biology". Univ Naples
1999-2000	Faculty of Plant Biotechnology, University of Naples: 20 hrs lab classes at the course “Genetic engineering of plant crops 
1998, 1999, 2000	Faculty of Agricultural Science and Technology Univ. of Naples: 30 hrs/year

Most relevant Invited talks

“Phostimulation of Semiconducting Nanoparticles to Control Physiological Functions In Vivo”. Invited speaker Symposium Fl, Biological, Biohybrid And Bioinspired Materials: From Electronics And Photonics To Medicine. CIMTEC 2018, 8th Forum on New Materials, Perugia 14 June 2018. Conference proceedings, FL-4:IL02, p 111

Semiconducting nanoparticles to modulate biological functions- lesson from an ancient model organism. Symposium BM3—Biological and Bioinspired Materials for Photonics and Electronics—From Living Organisms to Devices. MRS Fall Meeting. 27-11-2017. Boston, MA

 Probing animal biology by functional nanoparticles . 10th June 216,  CEA, Grenoble, France

Micro and Nano devices to control cell function. 13thApril 2016,  Institute for Microelectronics and Microsystems , Naples

Magnetic and optical hyperthermia in an invertebrate model system. 17th December 2014 IMEM-CNR, Parma, Italy

Ultrastructural evidence of entrance, trafficking and clearance of gold nanoparticles in a whole animal Cell Biology Seminars at SSSA: Vesicular Trafficking and Actin Remodeling”20-Feb-2014, Scuola Superiore Sant’Anna, Pisa. Italy

Unravelling animal biology by functional nanoparticles. 19-02-2014, Italian Institute of Technology, Genova, Italy.
 
Un nuovo organismo modello per la nanomedicina e la nanotossicologia. Workshop “Nuovi approcci in nanomedicina ed ingegneria tissutale” organized by INBB-UNINA-IIT-CIRM. 17 Sept 2013, Naples

Advanced nanotechnological tools to probe Hydra Biology. 12-03-2013 Internal seminars, Institute of Zoology, Univ of Innsbruck, Austria.

Functional nanoparticles to get new clues on animal biology. 25-03-2013. European Laboratory for Non Linear Spectroscopy, University of Florence, Italy. 

Effective silencing of the myc proto-oncogene through nanoparticle mediated RNA interference in Hydra vulgaris SPIE Photonic West: BioS Nanobiophotonic: Colloidal Quantum Dots/Nanocrystals for Biomedical Applications VII (Conference 8232). 22-01-2012, San Francisco.

An in vivo model system to test functional nanoparticles European Science Foundation EMRC/LESC/PESC  Exploratory Workshop on BioNanotechnology 2-09-2009 Sintra (Portugal). 

Un primitivo organismo modello per saggiare in vivo nanoparticelle fluorescenti di nuova generazione Workshop Federazione italiana Biotecnologi: 15-04- 2011 Rome, Italy.

Fate and functional outcomes of gold nanoparticles for in vivo gene silencing. WoMeN Workshop on Nanomedicine and Nanobiosystems. September 6-8 2012. Lecce, Italy

Gene silencing through nanoparticle mediated RNA interference in Hydra vulgaris". Spring meeting Dept of Biochemistry and Medical Biotechnology. 26-04-2012, University of Naples, Italy. 

AWARDS AND RESEARCH HIGHLIGHTS
2-2018	Results of scientific article Tortiglione et al (Sci Adv 2017) highlighted in Nature Nanotechnology News and Views:         “Light touch”, by G.Lanzani, and  
2-2017 	highlighted by national agencies: ANSA.tecnologie, ANSA Campania, Corriere Notizie, Virgilio, Rassegna stampa     CNR, ItalFimet

3-03-2017 	Results of Marie Curie project HyHeat highlighted by “Horizon: the EU research magazine”

4-03-2016 	Results of article Ambrosone et al ACS Nano 2016 highlighted on CNR news. 
                Results were also Highlighted in the Perspective article: Y. Zhang et al, ACS Nano 2016, 10 (4): 3881-3885

12-2013	BioPhotonic featured article: “Trends in Imaging: Whole-Animal Imaging for Preclinical Research “ Edited by M.Freebody (http://www.photonics.com/Article.aspx?AID=55523)

02/1996 – 05/1996	European Science Foundation Short mobility Research grant at Institute of Cell and Molecular Biology, University of Edinburgh, UK

16-01-2009 Highlighted by High tech-materials Alert by Frost & Sullivan: “Designing nanoparticles for stimulating neuronal activity (http://www.frost.com/srch/catalog-search.do?queryText=tortiglione) 

25-07-2007 Highlighted by the newspaper La Stampa as representative of emerging nanotechnologies developed at National Research Council for biomedical applications (http://archivio.lastampa.it)

PUBLICATIONS
2007-2019: go to  NanoBiomolecular Group Publication page

Former publications
Pierobon, P., Sogliano, C., Minei, R., Tino, A., Porcu, P., Marino, G., Tortiglione, C. and Concas, A. (2004). Putative NMDA receptors in Hydra: a biochemical and functional study. Eur J Neurosci 20, 2598-604.

Rao, R., Breuer, M., Tortiglione, C., Malva, C., Baggerman, G., Corrado, G., De Loof, A., and Pennacchio, F. (2004). Transgenic expression in tobacco of a poly-proctolin construct leading to production of the bioactive peptide. Biotechnology letters 26, 1413-1420.

Tortiglione, C., Fogliano, V., Ferracane, R., Fanti, P., Pennacchio, F., Monti, L. M. and Rao, R. (2003). An insect peptide engineered into the tomato prosystemin gene is released in transgenic tobacco plants and exerts biological activity. Plant Mol Biol 53, 891-902.

Tortiglione, C., Fanti, P, Pennacchio, F, Malva, C, Breuer, M, De Loof, A, Monti, L, Rao, R. (2002). The expression in tobacco plants of Aedes aegypti Trypsin Modulating Oostatic Factor (Aea-TMOF) alters growth and development of the tobacco budworm, Heliothis virescens. Molecular breeding 9, 159-169.

Tortiglione, C., Pennacchio, F., Rao, R. . (1999). Nuovi biopesticidi per la protezione delle colture dagli insetti fitofagi. . BIOTEC 4, 25-30.

Rotoli, D., Andone, S., Tortiglione, C., Manzi, A., Malva, C. and Graziani, F. (1998). hold up is required for establishment of oocyte positioning, follicle cell fate and egg polarity and cooperates with Egfr during Drosophila oogenesis. Genetics 148, 767-73.

Tortiglione, C., Bownes, M. (1997). Conservation and divergence in the control of a sex-differentiation gene in dipterans. Development Genes Evolution 207, 264-281.

Tortiglione, C., Malva, C., Pennacchio, F., Rao, R.  (1999). New Genes For Pest Control. In Genetics and breeding for crop quality and resistance,  (ed. G. T. S. M. E. P. E.A.Magnotta), pp. 159-163: Kluwer Academic Publisher 
http://www.scopus.com/authid/detail.url?authorId=6506714393http://orcid.org/0000-0003-1447-7611%22%20%5Co%20%22Click%20for%20public%20view%20of%20ORCID%20iDmailto:c.tortiglione@cib.na.cnr.itmailto:claudia.tortiglione@cnr.ithttp://www.photonics.com/Article.aspx?AID=55523http://www.frost.com/srch/catalog-search.do?queryText=tortiglionehttp://archivio.lastampa.itPublications.htmlshapeimage_1_link_0shapeimage_1_link_1shapeimage_1_link_2shapeimage_1_link_3shapeimage_1_link_4shapeimage_1_link_5shapeimage_1_link_6shapeimage_1_link_7

curriculum vitae

claudia tortiglione