Nanobiotechnology arises when biotechnological applications meet the nanoscale world introducing intriguing advances in biology and medicine. Multifunctional potential and tailorability of nanomaterials make them attractive for manifold purposes, from basic to applied biology. In this emerging field, we are interested in using engineered nanoparticles to deliver bioactive molecules (nucleic acids, drugs, peptides) and to test their biocompatibility, bioactivity and toxicity in vivo, using cnidarian model organisms